Kategori: Metin Çevirileri

İngilizce Metin Glycine plays an important role in cognitive functions along with glutamate. Glycine, acting as a glutamate agonist, may be useful in the treatment of negative symptoms of schizophrenia. Türkçe Çevirisi Glisin, glutamat ile birlikte bilişsel işlevlerde önemli bir rol oynar. Glutamat agonisti olarak hareket eden glisin, şizofreninin negatif semptomlarının tedavisinde yararlı olabilir.

İngilizce Metin NAA reduces glutamate secretion by creating an endogenous agonistic effect on glutamate receptors. It is also a metabolite of glutamate. NAA was found to be decreased in schizophrenia patients or those at risk. Türkçe Çevirisi Naa, glutamat reseptörleri üzerinde endojen agonistik bir etki yaratarak glutamat sekresyonunu azaltır. Aynı zamanda glutamatın bir metabolitidir. NAA, […]

İngilizce Metin LY354740, a synthetic agonist, blocks schizophrenia induced by the PCP model. This substance also prevents short-term memory impairment in schizophrenia. Low levels of glutamate play a role in the development of both positive and negative symptoms in schizophrenia. Lack of glutamate in the PFC and hippocampus causes an increase in dopaminergic activity by […]

İngilizce Metin Glutamate stimulates dopamine neurons. Glutamate NMDA receptor antagonists such as PCP and ketamine form psychosis-like experiences in normal individuals. Glutamate NMDA receptor antagonists exacerbate symptoms in patients with schizophrenia. Antipsychotics such as clozapine increase NMDA receptor expression. Glutamate Theory ın Schızophrenıa Türkçe Çevirisi Glutamat dopamin nöronlarını uyarır. Pcp ve ketamin gibi glutamat NMDA […]

İngilizce Metin DA receptor agonists (apomorphine) do not reveal psychosis. Although DA blockade is very rapid, positive symptoms calm down after weeks. Excessive dopamine does not explain all of the symptoms. Lack of activity of DA neurons in PFC causes mesolimbic dopaminergic neurons to get rid of inhibition. Türkçe Çevirisi Da reseptör agonistleri (apomorfin) psikozu […]

İngilizce Metin Dopamine agonists (cocaine, etc.) induce psychosis. L-DOPA exacerbates psychotic symptoms. There is association between D2 receptor antagonists’ DA binding capacity and antipsychotic effect. In post-mortem studies and PET studies, an increase in D2 DA and D4 DA receptors is observed. Türkçe Çevirisi Dopamin agonistleri (kokain, vb.) psikoza neden olur. L-DOPA psikotik semptomları şiddetlendirir. […]

İngilizce Metin Negative symptoms decrease and frontal lobe functions are normalized. Dopamine plays an important role in the information processing process required to distinguish the stimulus from noise. It makes fine tuning the information processing process in the prefrontal cortex. Excess DA input causes disruptive effect in the cortical information processing. Negative and cognitive symptoms […]

İngilizce Metin LSD and PCP antagonize 5HT2 receptors. These drugs reveals schizophrenia-like effects. Atypical Neuroleptics. Serotonin inhibits dopamine. Atypical drugs antagonize 5HT2 receptors in the cortex. Blocking dopamine inhibition by 5HT increases DA in the frontal lobe. Thus, DA increase in frontal lobes. Türkçe Çevirisi LSD ve PCP 5ht2 reseptörlerini antagonize eder. Bu ilaçlar şizofreni […]

İngilizce Metin Hypofrontality and schizophrenic symptoms: This figure hypothetically demonstrates the role of hypofrontality in the development of positive and negative symptoms of schizophrenia. Türkçe Çevirisi Hipofrontalite ve şizofrenik semptomlar: bu rakam varsayımsal olarak şizofreninin pozitif ve negatif semptomlarının gelişiminde hipofrontalitenin rolünü göstermektedir.

İngilizce Metin Direct administration of PCP to the prefrontal cortex increases the secretion of dopamine in the nucleus accumbens. Clozapine eliminates positive, negative, cognitive symptoms. It increases dopamine secretion in prefrontal cortex and decreases dopamine secretion in the nucleus accumbens. Schizophrenia occurs slowly. First, negative and then cognitive- lastly positive symptoms appear. Türkçe Çevirisi PCP’NİN […]

İngilizce Metin PCP and ketamine are indirect antagonists of NMDA receptors. It suppresses dorsolateral prefrontal cortex. It reduces dopamine utilization levels. Associated with negative and cognitive symptoms. Direct administration of PCP to the prefrontal cortex increases the secretion of dopamine in the nucleus accumbens. Türkçe Çevirisi PCP ve ketamin, NMDA reseptörlerinin dolaylı antagonistleridir. Dorsolateral prefrontal […]

İngilizce Metin How do atypical antipsychotics work, which can eliminate all three types of symptoms of schizophrenia? For example, aripiprazole works as a “partial agonist” of dopamine receptors. This drug acts as an antagonist for dopamine in nucleus accumbens, while it acts as an agonist for dopamine in the ventral tegmental area. Türkçe Çevirisi Şizofreni […]